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What will a biopsy involve. A biopsy is a sample of mouth tissue (eg lip, cheek, gum, tongue) that enables us to look at it under a microscope. We will use local anaesthetic to numb the area national identity card overseas pakistanis sew it up afterwards using dissolvable stitches (sutures). The biopsy area might be a little sore for a couple of days afterwards and you should rinse your mouth with warm salted water pakostanis a week to keep the area clean.